Experience the unmatched flavor and juiciness of turkey tenderloins cooked to perfection in a cast-iron skillet. This method ensures even heat distribution and a beautiful sear, locking in moisture and enhancing the dish with a rich, savory crust that’s simply irresistible.
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I absolutely love making this recipe because it’s incredibly simple yet yields delicious, healthy results. It’s a stress-free dish that allows me to focus on other tasks while it bakes, and the result is always a hit at the dinner table. This recipe helps me provide a nutritious meal for my loved ones without compromising on taste.
What You’ll Love About Turkey Tenderloins
- Tender and Juicy: Searing the tenderloins locks in the juices, ensuring each bite is tender and succulent.
- Easy Preparation: Simple steps and minimal ingredients make it a breeze to prepare.
- Impressive Presentation: The beautifully seared and seasoned tenderloins make for a really pretty presentation.

Ingredients and Estimated Cost:
- 2 turkey tenderloins – $9.82
- ⅓ cup olive oil – $0.74
- 2 teaspoons paprika – $0.08
- 2 teaspoons poultry seasoning – $0.38
- ½ teaspoon salt – $0.01
- ½ teaspoon pepper – $0.05
NOTE: The recipe prices are calculated by using grocery store websites. The actual cost of the recipe will vary depending on what ingredients you already have. I updated the prices for this recipe in August 2024.

How To Make Turkey Tenderloin
***For complete recipe instructions, see the recipe card below.
Prepare Tenderloins
- Mix paprika, poultry seasoning, salt, and pepper in a bowl.
- Pat tenderloins dry with a paper towel.
- Rub seasoning mixture on all sides of tenderloins.

Cook Tenderloins
- Heat oil in a cast iron skillet.
- Sear tenderloins on each side for 1 minute.
- Cover the skillet with a lid and cook in a 300 degrees F oven for 30-35 minutes or until internal temperature reaches 160 degrees F.

Rest and Serve
- Let tenderloins rest for 5-10 minutes before slicing and serving.

Equipment
- Measuring cups and spoons
- Cast Iron Skillet
- Tongs
- Instant-read thermometer
Storage Tips
Store: Place cooked turkey tenderloins in an airtight container or wrap them tightly in aluminum foil. Refrigerate for up to 3-4 days.
Freeze: Once cooled, wrap the turkey tenderloins in plastic wrap and aluminum foil or place them in a freezer-safe bag. Label and freeze for up to 3 months.
Thaw: Transfer the frozen turkey tenderloins to the refrigerator and allow them to thaw overnight. Use the defrost setting on a microwave for a quicker option, but be careful not to start cooking the turkey.
Reheat: Preheat your oven to 350°F (175°C). Place the thawed turkey tenderloins in an oven-safe dish, cover with foil, and heat for about 20-25 minutes or until warmed. Alternatively, reheat in the microwave on medium power, checking every minute until heated.
Recipe FAQs
What can I serve with these tenderloins?
These tenderloins pair well with various sides, such as Cauliflower Fried Rice, Roasted Carrot Fries, Crispy Roasted Potatoes, and a Spinach Caprese Salad.
Can I use a different type of oil for searing?
Sure! Olive oil, avocado oil, or any high-heat cooking oil will work well for searing the tenderloins.
How can I tell when the tenderloins are done?
Use an instant-read thermometer to ensure the internal temperature reaches 160°F. The tenderloins should be firm to the touch but still juicy.
What if I don’t have a cast iron skillet?
You can use any oven-safe skillet or transfer the seared tenderloins to a baking dish before placing them in the oven.

More Dinner Recipes
- Mexican Grilled Chicken
- Healthy Tuscan Chicken
- Easy Baked Chicken and Zucchini Recipe
- Chinese Chicken and Broccoli
- Ginger Chicken Skewers

Turkey Tenderloin
Ingredients
- 2 Turkey Tenderloins about ¾ lb each
- ⅓ cup olive oil
- 2 teaspoons paprika
- 2 teaspoons poultry seasoning
- ½ teaspoon salt
- ½ teaspoon pepper
Instructions
- Preheat the oven to 300℉.
- Add the paprika, poultry seasoning, salt, and pepper to a bowl and mix until incorporated.
- Pat the tenderloins dry with a paper towel.
- Rub the tenderloins on each side with the seasoning mixture.
- In a cast iron skillet, heat the oil over medium-high heat.
- Sear the tenderloins on each side for 1 minute.
- Place the lid on the skillet and bake for 30-35 minutes, or until the tenderloins register 160℉ on an instant-read thermometer.
- Take the tenderloins out and let them rest for 5-10 minutes. Serve and enjoy!
Equipment
Nutrition
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